Substances (GSRS)

ARSONODITHIOUS ACID, AS-(4-((4,6-DIAMINO-1,3,5-TRIAZIN-2-YL)AMINO)PHENYL)-, BIS(2-AMINOETHYL) ESTER

Also: BIS(2-AMINOETHYL) P-((4,6-DIAMINO-S-TRIAZIN-2-YL)AMINO)DITHIOBENZENEARSONITE, MELARSAMIN, MELARSOMINE +3

chemicalUNII 374GJ0S41A

Open FDA's page for this record

Substance class

chemical

Definition type

PRIMARY

Definition level

COMPLETE

Uuid

74ad0994-18f0-48c7-b306-c0379cd52bea

Version

UNII

374GJ0S41A

Codes

Uuid
abbf8e2c-edf2-4dff-8847-da7372105b37
Code
QP51AD06
Comments
VATC|ANTIPROTOZOALS|AGENTS AGAINST PROTOZOAL DISEASES|Arsenic compounds|melarsamin
Type
PRIMARY
Url
http://www.whocc.no/atcvet/atcvet_index/?code=QP51AD06&showdescription=yes
Code system
WHO-VATC
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
607c3c1f-1513-4e0c-9d2b-429af20ff99a
Code
128470-15-5
Type
PRIMARY
Url
https://commonchemistry.cas.org/detail?cas_rn=128470-15-5
Code system
CAS
References
364d5e83-b150-4255-885a-c04f3e0bf16f, bb9efa1d-579b-4f4b-ba51-97cec03814d0
Uuid
75428a8e-c7ec-4b05-af79-d22bd17883fd
Code
C66078
Type
PRIMARY
Url
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C66078
Code system
NCI_THESAURUS
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
f3bfdf8a-bf5a-4e8e-93cf-c9af5b3ef24e
Code
C076253
Type
PRIMARY
Url
http://www.ncbi.nlm.nih.gov/mesh/67076253
Code system
MESH
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
983217a2-bf3d-4dcf-a142-f05297cd383a
Code
MELARSOMINE
Type
PRIMARY
Url
https://en.wikipedia.org/wiki/Melarsomine
Code system
WIKIPEDIA
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
f2d23c1c-6985-4d98-b843-bce9d6a97891
Code
SUB08719MIG
Type
PRIMARY
Code system
EVMPD
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
df52c2f0-f8ce-4cb1-b6c5-d21e93626f33
Code
6676
Type
PRIMARY
Url
https://extranet.who.int/soinn/mod/page/view.php?id=137&inn_n=6676
Code system
INN
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
bb531d27-4971-4bba-88a3-b437a1c12a97
Code
1012534
Comments
RxNorm
Type
PRIMARY
Url
https://rxnav.nlm.nih.gov/REST/rxcui/1012534/allProperties.xml?prop=all
Code system
RXCUI
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
63b5c5cb-86fd-4287-bd70-6fc00e554017
Code
65962
Type
PRIMARY
Url
https://pubchem.ncbi.nlm.nih.gov/compound/65962
Code system
PUBCHEM
References
364d5e83-b150-4255-885a-c04f3e0bf16f
Uuid
bc01677d-3973-7f02-14a7-cefc59cf7499
Code
DTXSID40155907
Type
PRIMARY
Url
https://comptox.epa.gov/dashboard/chemical/details/DTXSID40155907
Code system
EPA CompTox
References
6caecc90-a177-0728-7669-65eabab7e4d7
Uuid
98a729aa-1aae-d553-22e8-aaf1f016eec0
Code
C250
Comments
Pharmacologic Substance[C1909]|Anti-Infective Agent[C254]|Antiparasitic Agent[C276]|Antihelminthic Agent
Type
CONCEPT
Url
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C250
Code system
NCI_THESAURUS
References
d1a13be0-4878-2a2c-20bc-b16da04e7a4c
Uuid
b2099abd-1dd6-41d7-83a2-0ba37f9bbf71
Code
374GJ0S41A
Type
PRIMARY
Code system
FDA UNII
+3 more not shown

Relationships

Uuid
3cbf0019-3bff-44de-8b66-256f60c6fd4f
Type
ACTIVE MOIETY
Related substance
Uuid
ecb68fa7-a269-45a3-a884-840f1ea338fd
Refuuid
74ad0994-18f0-48c7-b306-c0379cd52bea
Name
MELARSOMINE
UNII
374GJ0S41A
Linking ID
374GJ0S41A
Ref pname
MELARSOMINE
Substance class
reference
Uuid
085e02f9-56d9-48b6-ac6c-57e49232f748
Type
SALT/SOLVATE->PARENT
Related substance
Uuid
31932342-c5c1-4706-a9b8-2b640fdbfc1e
Refuuid
26764330-6062-44ed-a03a-8a83e4f3b4b2
Name
MELARSOMINE DIHYDROCHLORIDE
UNII
9CVA716Q71
Linking ID
9CVA716Q71
Ref pname
MELARSOMINE DIHYDROCHLORIDE
Substance class
reference

Names

Uuid
3f57b942-e5a0-48e5-a28d-6c1f523e8f98
Name
ARSONODITHIOUS ACID, AS-(4-((4,6-DIAMINO-1,3,5-TRIAZIN-2-YL)AMINO)PHENYL)-, BIS(2-AMINOETHYL) ESTER
StdName
ARSONODITHIOUS ACID, AS-(4-((4,6-DIAMINO-1,3,5-TRIAZIN-2-YL)AMINO)PHENYL)-, BIS(2-AMINOETHYL) ESTER
Type
cn
Preferred
false
Display name
false
Languages
en
References
73b993e7-4e6a-4908-a359-80708b47e599, ffdef803-ca95-49f9-9f32-b636937ca6e6
Uuid
dfd07ba5-54f6-4049-ad96-5ef0ff093f5e
Name
BIS(2-AMINOETHYL) P-((4,6-DIAMINO-S-TRIAZIN-2-YL)AMINO)DITHIOBENZENEARSONITE
StdName
BIS(2-AMINOETHYL) P-((4,6-DIAMINO-S-TRIAZIN-2-YL)AMINO)DITHIOBENZENEARSONITE
Type
cn
Preferred
false
Display name
false
Languages
en
References
5f912709-6ccc-40e2-a94e-1bbcad118a60
Uuid
4c8ccb06-7bb6-4de3-a4f5-14a9e64f5523
Name
MELARSAMIN
StdName
MELARSAMIN
Type
cn
Preferred
false
Display name
false
Languages
en
References
87084d16-f2d2-458e-8cae-f19f69322749, ffdef803-ca95-49f9-9f32-b636937ca6e6
Uuid
f3a50a38-6bcc-4380-8f43-4252cd579bea
Name
MELARSOMINE
StdName
MELARSOMINE
Type
of
Preferred
false
Display name
true
Languages
en
References
0f715102-fd29-44d8-bb61-dc913ba576ad, e581ffd8-c1dc-4e4d-8574-f3f307f93a0d, b31fe0cf-d892-499e-b80e-049831ea54c6, f64602cd-6057-4151-8eb9-80b2ede2f87c, 9494cb8c-3f65-42bc-aef5-60cbb4ac9c92
Domains
drug
Name orgs
1. Uuid
  d74928fc-5ebc-4587-9e06-cc180221d054
  Name org
  INN
Uuid
b0aa56a5-339c-4350-ac68-5388eb09feec
Name
MELARSOMINE [MART.]
StdName
MELARSOMINE [MART.]
Type
cn
Preferred
false
Display name
false
Languages
en
References
b31fe0cf-d892-499e-b80e-049831ea54c6
Uuid
be684594-717c-22eb-83ea-c045fb3701ae
Name
MELARSOMINE [MI]
StdName
MELARSOMINE [MI]
Type
cn
Preferred
false
Display name
false
Languages
en
References
9a8ffb5a-507c-7e91-0ce5-2fd72f62d68e
Uuid
0b13d16a-5596-47ec-a32d-d2127023fab4
Name
melarsomine [INN]
StdName
MELARSOMINE [INN]
Type
cn
Preferred
false
Display name
false
Languages
en
References
f64602cd-6057-4151-8eb9-80b2ede2f87c

References

Uuid
e581ffd8-c1dc-4e4d-8574-f3f307f93a0d
Citation
USP Dictionary 2009
Doc type
SRS
Public domain
true
Tags
NOMEN, PUBLIC_DOMAIN_RELEASE, AUTO_SELECTED
Uuid
5f912709-6ccc-40e2-a94e-1bbcad118a60
Citation
USP DICTIONARY 2009
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
73b993e7-4e6a-4908-a359-80708b47e599
Citation
STN
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
ffdef803-ca95-49f9-9f32-b636937ca6e6
Citation
STN (SCIFINDER)
Doc type
STN (SCIFINDER)
Public domain
true
Tags
NOMEN
Uuid
f64602cd-6057-4151-8eb9-80b2ede2f87c
Citation
INN Proposed List 64
Url
https://www.who.int/medicines/publications/druginformation/innlists/PL64.pdf
Doc type
INN_LIST
Public domain
true
Tags
PUBLIC_DOMAIN_RELEASE
Uuid
b31fe0cf-d892-499e-b80e-049831ea54c6
Citation
MARTINDALE 2011
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
87084d16-f2d2-458e-8cae-f19f69322749
Citation
VATC
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
364d5e83-b150-4255-885a-c04f3e0bf16f
Citation
SRS CODE IMPORT
Doc type
SRS
Public domain
true
Document date
1493390693000
Tags
NOMEN
Uuid
fe022879-4972-4e5e-967b-ba9703973e82
Citation
SRS import [374GJ0S41A]
Url
http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=374GJ0S41A
Doc type
SRS
Public domain
true
Document date
1493390693000
Tags
NOMEN
Uuid
0f715102-fd29-44d8-bb61-dc913ba576ad
Citation
MELARSOMINE [INN]
Doc type
SRS_LOCATOR
Public domain
true
Uuid
9494cb8c-3f65-42bc-aef5-60cbb4ac9c92
Citation
MELARSOMINE [MART.]
Doc type
SRS_LOCATOR
Public domain
true
Uuid
6caecc90-a177-0728-7669-65eabab7e4d7
Citation
WEBSITE
Url
https://comptox.epa.gov/dashboard/dsstoxdb/results?utf8=%E2%9C%93&search=128470-15-5
Doc type
WEBSITE
Public domain
true
Tags
NOMEN, PUBLIC_DOMAIN_RELEASE
+5 more not shown

Moieties

Uuid
458e7c35-94a3-4781-8ba5-04499ef3c157
ID
458e7c35-94a3-4781-8ba5-04499ef3c157
Smiles
c1cc(ccc1[As](SCCN)SCCN)Nc2nc(N)nc(N)n2
Formula
C13H21AsN8S2
Atropisomerism
No
Charge
0
Count
1
Stereochemistry
ACHIRAL
Defined stereo
0
Ez centers
0
Molecular weight
428.4137
Optical activity
NONE
Stereo centers
0
Molfile
Marvin 01132103392D 24 25 0 0 0 0 999 V2000 5.4557 -1.3222 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 4.7424 -0.9092 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0292 -1.3264 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.3160 -0.9135 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 2.4526 -1.4057 0.0000 As 0 0 0 0 0 0 0 0 0 0 0 0 2.4484 -2.2315 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 3.1616 -2.6445 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8748 -2.2273 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5881 -2.6403 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.7408 -0.9936 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0257 -1.4050 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3132 -0.9920 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3170 -0.1669 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3962 0.2461 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1063 -0.1710 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8190 0.2461 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5318 -0.1710 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2492 0.2420 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5318 -0.9968 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.8190 -1.4057 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8269 -2.2315 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1063 -0.9968 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.0262 0.2439 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7392 -0.1652 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 3 2 1 0 0 0 0 4 3 1 0 0 0 0 5 4 1 0 0 0 0 5 6 1 0 0 0 0 10 5 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 8 9 1 0 0 0 0 11 10 1 0 0 0 0 10 24 2 0 0 0 0 12 11 2 0 0 0 0 13 12 1 0 0 0 0 14 13 1 0 0 0 0 23 13 2 0 0 0 0 15 14 1 0 0 0 0 15 16 1 0 0 0 0 22 15 2 0 0 0 0 17 16 2 0 0 0 0 17 18 1 0 0 0 0 17 19 1 0 0 0 0 19 20 2 0 0 0 0 20 21 1 0 0 0 0 20 22 1 0 0 0 0 24 23 1 0 0 0 0 M END
Count amount
Type
MOL RATIO
Average
1
Units
MOL RATIO
Uuid
95ec326b-85b8-404e-8745-655e82df4280

Structure

ID: bd827175-e891-4ded-bae6-139e33368478
Smiles: c1cc(ccc1[As](SCCN)SCCN)Nc2nc(N)nc(N)n2
Formula: C13H21AsN8S2
Atropisomerism: No
Charge: 0
Count: 1
Stereochemistry: ACHIRAL
Defined stereo: 0
Ez centers: 0
Molecular weight: 428.4137
Optical activity: NONE
Stereo centers: 0
Molfile: Marvin 01132109482D 24 25 0 0 0 0 999 V2000 -2.5318 -0.1710 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5318 -0.9968 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.8190 -1.4057 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.1063 -0.9968 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.1063 -0.1710 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.8190 0.2461 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -3.2492 0.2420 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -1.8269 -2.2315 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3962 0.2461 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 0.3170 -0.1669 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3132 -0.9920 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0257 -1.4050 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7408 -0.9936 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7392 -0.1652 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.0262 0.2439 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.4526 -1.4057 0.0000 As 0 0 0 0 0 0 0 0 0 0 0 0 3.3160 -0.9135 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 4.0292 -1.3264 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7424 -0.9092 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4557 -1.3222 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.4484 -2.2315 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 3.1616 -2.6445 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.8748 -2.2273 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5881 -2.6403 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 11 12 1 0 0 0 0 5 6 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 1 7 1 0 0 0 0 14 15 2 0 0 0 0 15 10 1 0 0 0 0 1 2 1 0 0 0 0 13 16 1 0 0 0 0 3 8 1 0 0 0 0 16 17 1 0 0 0 0 1 6 2 0 0 0 0 17 18 1 0 0 0 0 5 9 1 0 0 0 0 18 19 1 0 0 0 0 2 3 2 0 0 0 0 19 20 1 0 0 0 0 9 10 1 0 0 0 0 16 21 1 0 0 0 0 3 4 1 0 0 0 0 21 22 1 0 0 0 0 10 11 2 0 0 0 0 22 23 1 0 0 0 0 4 5 2 0 0 0 0 23 24 1 0 0 0 0 M END
References: e581ffd8-c1dc-4e4d-8574-f3f307f93a0d, fe022879-4972-4e5e-967b-ba9703973e82, f64602cd-6057-4151-8eb9-80b2ede2f87c

Data from openFDA, FDA's public API. FDA says not to rely on it to make decisions about medical care and to treat every result as unvalidated; confirm against FDA's own record and the product labeling. Not medical or legal advice.