2-CHLORO-4'-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PROPIONANILIDE
Also: AMIPIZONE, amipizone [INN]
Open FDA's page for this record- Substance class
- chemical
- Definition type
- PRIMARY
- Definition level
- COMPLETE
- Uuid
- 38ac3dd5-b273-49ea-a4f9-3f152e6719fa
- Version
- 6
- UNII
- 7OT95Q2G4E
- Codes
- Uuid
- c7ec6473-b785-4d9c-ad99-b2ef7ce57b76
- Code
- 69635-63-8
- Type
- PRIMARY
- Url
- https://commonchemistry.cas.org/detail?cas_rn=69635-63-8
- Code system
- CAS
- References
- c7330111-a72e-46fc-92b1-b58dc3d36861, d43105fd-5eee-4553-b74d-3cb365b6b301
- Uuid
- e71c0117-a8ce-4da4-b7e4-35e60999af72
- Code
- C74345
- Type
- PRIMARY
- Url
- https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C74345
- Code system
- NCI_THESAURUS
- References
- c7330111-a72e-46fc-92b1-b58dc3d36861
- Uuid
- 6be8652c-377c-4cb3-91cd-e67db6a3d891
- Code
- SUB05454MIG
- Type
- PRIMARY
- Code system
- EVMPD
- References
- c7330111-a72e-46fc-92b1-b58dc3d36861
- Uuid
- a83a5296-ee2a-475f-a509-9a412b8092dc
- Code
- 5024
- Type
- PRIMARY
- Url
- https://extranet.who.int/soinn/mod/page/view.php?id=137&inn_n=5024
- Code system
- INN
- References
- c7330111-a72e-46fc-92b1-b58dc3d36861
- Uuid
- 19da0f92-b26f-44ee-989f-ccfc95289bd7
- Code
- CHEMBL116368
- Type
- PRIMARY
- Url
- https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL116368
- Code system
- ChEMBL
- References
- c7330111-a72e-46fc-92b1-b58dc3d36861
- Uuid
- b9195774-62bd-4cf3-8403-e3578d058e3b
- Code
- 68889
- Type
- PRIMARY
- Url
- https://pubchem.ncbi.nlm.nih.gov/compound/68889
- Code system
- PUBCHEM
- References
- c7330111-a72e-46fc-92b1-b58dc3d36861
- Uuid
- 4ffbe0f9-e59c-b59a-9231-4c330b7b41b3
- Code
- C744
- Comments
- Pharmacologic Substance[C1909]|Enzyme Inhibitor[C471]|Phosphodiesterase Inhibitor
- Type
- CONCEPT
- Url
- https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C744
- Code system
- NCI_THESAURUS
- References
- cfe5a8c8-99c1-27ab-66f0-59d7d777d9c5
- Uuid
- 8549d34e-57cb-4dc3-9e59-51d06caed751
- Code
- 7OT95Q2G4E
- Type
- PRIMARY
- Code system
- FDA UNII
- Uuid
- b2040b77-395f-e3a0-4b99-d2c5f25722f1
- Code
- 100000087212
- Type
- PRIMARY
- Code system
- SMS_ID
- References
- 349f4c04-753c-809c-037f-393449d8030a
- Uuid
- 4535dee9-56d0-3500-8b6c-5a35504d883f
- Code
- DTXSID30867840
- Type
- PRIMARY
- Url
- https://comptox.epa.gov/dashboard/chemical/details/DTXSID30867840
- Code system
- EPA CompTox
- References
- cfe5a8c8-99c1-27ab-66f0-59d7d777d9c5
- Relationships
- Uuid
- 581188c8-be25-4e6d-a74e-9e07d4ab0edc
- Type
- ACTIVE MOIETY
- Related substance
- Uuid
- 9ab52744-35a3-4beb-b353-66adfafc4ebd
- Refuuid
- 38ac3dd5-b273-49ea-a4f9-3f152e6719fa
- Name
- AMIPIZONE
- UNII
- 7OT95Q2G4E
- Linking ID
- 7OT95Q2G4E
- Ref pname
- AMIPIZONE
- Substance class
- reference
- Names
- Uuid
- c1ccfe96-002d-4d84-af0e-48974570c5ed
- Name
- 2-CHLORO-4'-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PROPIONANILIDE
- StdName
- 2-CHLORO-4'-(1,4,5,6-TETRAHYDRO-4-METHYL-6-OXO-3-PYRIDAZINYL)PROPIONANILIDE
- Type
- sys
- Preferred
- false
- Display name
- false
- Languages
- en
- References
- 69e9c141-63b5-42fe-a30d-65d380af1c15
- Uuid
- 998370af-6462-442f-9780-2d43bd7907cc
- Name
- AMIPIZONE
- StdName
- AMIPIZONE
- Type
- of
- Preferred
- false
- Display name
- true
- Languages
- en
- References
- 2acfe6c9-8ff4-45fa-987a-6c8deb115005, 69e9c141-63b5-42fe-a30d-65d380af1c15, 443c4ab1-c5fe-490b-9ba3-5a7c16f93dd8
- Domains
- drug
- Name orgs
- Uuid
- a649ab48-2a31-4220-a98d-89fde08ccddd
- Name org
- INN
- Uuid
- 3ad602e0-4d96-4cf3-8930-69f1157c6890
- Name
- amipizone [INN]
- StdName
- AMIPIZONE [INN]
- Type
- cn
- Preferred
- false
- Display name
- false
- Languages
- en
- References
- 2acfe6c9-8ff4-45fa-987a-6c8deb115005
- References
- Uuid
- 69e9c141-63b5-42fe-a30d-65d380af1c15
- Citation
- USP Dictionary 2010
- Doc type
- SRS
- Public domain
- true
- Tags
- NOMEN, PUBLIC_DOMAIN_RELEASE, AUTO_SELECTED
- Uuid
- 2acfe6c9-8ff4-45fa-987a-6c8deb115005
- Citation
- INN Proposed List 45
- Url
- https://www.who.int/medicines/publications/druginformation/innlists/PL45.pdf
- Doc type
- INN_LIST
- Public domain
- true
- Tags
- PUBLIC_DOMAIN_RELEASE
- Uuid
- c7330111-a72e-46fc-92b1-b58dc3d36861
- Citation
- SRS CODE IMPORT
- Doc type
- SRS
- Public domain
- true
- Document date
- 1493390758000
- Tags
- NOMEN
- Uuid
- 7cc38724-d396-4a3f-ba7e-df60179dba0d
- Citation
- SRS import [7OT95Q2G4E]
- Url
- http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=7OT95Q2G4E
- Doc type
- SRS
- Public domain
- true
- Document date
- 1493390758000
- Tags
- NOMEN
- Uuid
- 443c4ab1-c5fe-490b-9ba3-5a7c16f93dd8
- Citation
- AMIPIZONE [INN]
- Doc type
- SRS_LOCATOR
- Public domain
- true
- Uuid
- cfe5a8c8-99c1-27ab-66f0-59d7d777d9c5
- Doc type
- SYSTEM
- Public domain
- true
- Uuid
- d43105fd-5eee-4553-b74d-3cb365b6b301
- Citation
- STN
- Doc type
- STN (SCIFINDER)
- Public domain
- true
- Uuid
- 349f4c04-753c-809c-037f-393449d8030a
- Citation
- EU-SRS
- Doc type
- EMA LIST
- Public domain
- true
- Moieties
- Uuid
- a84e23bd-0bc7-4ece-9e5d-515f55b461a2
- ID
- a84e23bd-0bc7-4ece-9e5d-515f55b461a2
- Smiles
- CC1CC(=O)NN=C1c2ccc(cc2)NC(=O)C(C)Cl
- Formula
- C14H16ClN3O2
- Atropisomerism
- No
- Charge
- 0
- Count
- 1
- Stereochemistry
- MIXED
- Defined stereo
- 0
- Ez centers
- 0
- Molecular weight
- 293.7492
- Optical activity
- UNSPECIFIED
- Stereo centers
- 2
- Molfile
Marvin 01132108442D 20 21 0 0 0 0 999 V2000 9.7034 -5.9498 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9894 -5.5365 0.0000 C 0 0 0 0 0 0 0 0 0 3 0 0 8.9853 -4.7097 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 8.2754 -5.9540 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2772 -6.7807 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.5614 -5.5407 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.8490 -5.9609 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8547 -6.7861 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1444 -7.2029 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4279 -6.7933 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4196 -5.9736 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1270 -5.5543 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7172 -7.2107 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0037 -6.7933 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2901 -7.2107 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2901 -8.0374 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5720 -8.4467 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.0037 -8.4467 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7172 -8.0374 0.0000 C 0 0 0 0 0 0 0 0 0 3 0 0 5.4279 -8.4508 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 2 3 1 0 0 0 0 4 2 1 0 0 0 0 4 5 2 0 0 0 0 6 4 1 0 0 0 0 7 6 1 0 0 0 0 8 7 1 0 0 0 0 7 12 2 0 0 0 0 9 8 2 0 0 0 0 10 9 1 0 0 0 0 11 10 2 0 0 0 0 13 10 1 0 0 0 0 12 11 1 0 0 0 0 13 14 2 0 0 0 0 19 13 1 0 0 0 0 15 14 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 16 18 1 0 0 0 0 18 19 1 0 0 0 0 19 20 1 0 0 0 0 M END
- Count amount
- Type
- MOL RATIO
- Average
- 1
- Units
- MOL RATIO
- Uuid
- 8d5d4b4b-7ebd-441c-81a6-aa75242e94bf
- Structure
- ID
- 49b332a6-952e-472c-9d30-57aef4597689
- Smiles
- CC1CC(=O)NN=C1c2ccc(cc2)NC(=O)C(C)Cl
- Formula
- C14H16ClN3O2
- Atropisomerism
- No
- Charge
- 0
- Count
- 1
- Stereochemistry
- MIXED
- Defined stereo
- 0
- Ez centers
- 0
- Molecular weight
- 293.7492
- Optical activity
- UNSPECIFIED
- Stereo centers
- 2
- Molfile
Marvin 01132103512D 20 21 0 0 0 0 999 V2000 3.2901 -7.2107 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2901 -8.0374 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0037 -8.4467 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7172 -8.0374 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.7172 -7.2107 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0037 -6.7933 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.5720 -8.4467 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.4279 -8.4508 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4279 -6.7933 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1444 -7.2029 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8547 -6.7861 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8490 -5.9609 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.1270 -5.5543 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4196 -5.9736 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5614 -5.5407 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.2754 -5.9540 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9894 -5.5365 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9853 -4.7097 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 9.7034 -5.9498 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2772 -6.7807 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 9 10 2 0 0 0 0 3 4 1 0 0 0 0 10 11 1 0 0 0 0 4 5 1 0 0 0 0 11 12 2 0 0 0 0 5 6 2 0 0 0 0 12 13 1 0 0 0 0 13 14 2 0 0 0 0 14 9 1 0 0 0 0 2 7 2 0 0 0 0 12 15 1 0 0 0 0 1 2 1 0 0 0 0 15 16 1 0 0 0 0 4 8 1 0 0 0 0 1 6 1 0 0 0 0 16 17 1 0 0 0 0 5 9 1 0 0 0 0 17 18 1 0 0 0 0 2 3 1 0 0 0 0 17 19 1 0 0 0 0 16 20 2 0 0 0 0 M END
- References
- 69e9c141-63b5-42fe-a30d-65d380af1c15, 7cc38724-d396-4a3f-ba7e-df60179dba0d, 2acfe6c9-8ff4-45fa-987a-6c8deb115005