Substances (GSRS)

1H-Benzimidazole-7-carboxylic acid, 1-[(2′-carboxy[1,1′-biphenyl]-4-yl)methyl]-2-ethoxy-, 7-methyl…

Also: 7-Methyl 1-[(2′-carboxy[1,1′-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate, Azilsartan Impurity 6

chemicalUNII JQ9SD8DA8Q

Open FDA's page for this record

Substance class

chemical

Definition type

PRIMARY

Definition level

COMPLETE

Uuid

12d69a03-45f4-4b6b-8f83-641748e22d94

Version

UNII

JQ9SD8DA8Q

Codes

Uuid
780d7f5e-6171-4b56-88f2-b05055ce92b1
Code
1675221-59-6
Type
PRIMARY
Url
https://commonchemistry.cas.org/detail?cas_rn=1675221-59-6
Code system
CAS
References
a5a38e01-76af-44ab-96ce-6a0f283c2496
Uuid
71081851-8c25-78b9-147f-b97e1c344cff
Code
135742044
Type
PRIMARY
Url
https://pubchem.ncbi.nlm.nih.gov/compound/135742044
Code system
PUBCHEM
References
8886672f-f643-65dd-d6b9-0ed0481c34a9
Uuid
40814d6d-0cb9-49db-8c9b-037ed7620e96
Code
JQ9SD8DA8Q
Type
PRIMARY
Code system
FDA UNII

Names

Uuid
3a362369-aaac-4ab7-a539-e13fec36e4d2
Name
1H-Benzimidazole-7-carboxylic acid, 1-[(2′-carboxy[1,1′-biphenyl]-4-yl)methyl]-2-ethoxy-, 7-methyl ester
StdName
1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID, 1-((2'-CARBOXY(1,1'-BIPHENYL)-4-YL)METHYL)-2-ETHOXY-, 7-METHYL ESTER
Type
sys
Preferred
false
Display name
false
Languages
en
References
a5a38e01-76af-44ab-96ce-6a0f283c2496
Uuid
a2bd55a4-bb29-49eb-a65f-3014089ba643
Name
7-Methyl 1-[(2′-carboxy[1,1′-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
StdName
7-METHYL 1-((2'-CARBOXY(1,1'-BIPHENYL)-4-YL)METHYL)-2-ETHOXY-1H-BENZIMIDAZOLE-7-CARBOXYLATE
Type
sys
Preferred
false
Display name
true
Languages
en
References
a5a38e01-76af-44ab-96ce-6a0f283c2496
Uuid
ca5ddb3b-f5b9-4146-b83e-a778621e091d
Name
Azilsartan Impurity 6
StdName
AZILSARTAN IMPURITY 6
Type
cn
Preferred
false
Display name
false
Languages
en
References
8d5ebbe8-ad6d-4116-ab86-fff1386490af

References

Uuid
8886672f-f643-65dd-d6b9-0ed0481c34a9
Citation
PUBCHEM
Doc type
PUBCHEM
Public domain
true
Uuid
a5a38e01-76af-44ab-96ce-6a0f283c2496
Citation
STN
Doc type
STN (SCIFINDER)
Public domain
true
Tags
PUBLIC_DOMAIN_RELEASE
Uuid
8d5ebbe8-ad6d-4116-ab86-fff1386490af
Citation
SRS
Doc type
SRS
Public domain
true
Tags
PUBLIC_DOMAIN_RELEASE

Moieties

Uuid
1b9b9b1e-2e04-4475-9e60-5659ddd00462
ID
1b9b9b1e-2e04-4475-9e60-5659ddd00462
Smiles
CCOc1nc2cccc(c2n1Cc3ccc(cc3)-c4ccccc4C(=O)O)C(=O)OC
Formula
C25H22N2O5
Atropisomerism
No
Charge
0
Count
1
Stereochemistry
ACHIRAL
Defined stereo
0
Ez centers
0
Molecular weight
430.4535
Optical activity
NONE
Stereo centers
0
Molfile
CDK 04182314122D 32 35 0 0 0 0 0 0 0 0999 V2000 5.2308 4.0011 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.1051 2.9590 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.9605 1.9286 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.5696 2.4831 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.2807 0.4221 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5936 7.0619 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 7.0695 8.5266 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5759 8.8468 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3909 1.3338 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8509 1.3338 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 12.1609 0.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.9293 5.4959 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4608 5.3348 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.6091 7.0022 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.7849 4.4653 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0873 6.7418 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9428 7.7722 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1444 7.4780 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.3202 4.9413 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.4476 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.7709 4.0011 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5409 5.3348 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.5409 2.6675 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0809 5.3348 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.0809 2.6675 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.8509 4.0011 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.3909 4.0011 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1609 2.6675 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.1609 5.3348 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7010 2.6675 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.7010 5.3348 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 14.4710 4.0011 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1 13 1 0 0 0 0 1 21 1 0 0 0 0 2 3 1 0 0 0 0 2 4 2 0 0 0 0 2 15 1 0 0 0 0 3 5 1 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 8 1 0 0 0 0 9 10 1 0 0 0 0 9 11 2 0 0 0 0 9 28 1 0 0 0 0 12 13 1 0 0 0 0 12 14 1 0 0 0 0 12 15 2 0 0 0 0 13 16 1 0 0 0 0 14 17 1 0 0 0 0 14 18 2 0 0 0 0 15 19 1 0 0 0 0 16 17 2 0 0 0 0 18 20 1 0 0 0 0 19 20 2 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 24 1 0 0 0 0 23 25 2 0 0 0 0 24 26 2 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 28 30 1 0 0 0 0 29 31 2 0 0 0 0 30 32 2 0 0 0 0 31 32 1 0 0 0 0 M END
Count amount
Type
MOL RATIO
Average
1
Units
MOL RATIO
Uuid
271d8610-c005-4c91-9927-acc11eaa4483

Structure

ID: f20591cf-5632-4a44-b125-f9a0a424f33d
Smiles: CCOc1nc2cccc(c2n1Cc3ccc(cc3)-c4ccccc4C(=O)O)C(=O)OC
Formula: C25H22N2O5
Atropisomerism: No
Charge: 0
Count: 1
Stereochemistry: ACHIRAL
Defined stereo: 0
Ez centers: 0
Molecular weight: 430.4535
Optical activity: NONE
Stereo centers: 0
Molfile: 7-Methyl 1-[(2'-carboxy[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzimidazole... JSDraw204182310122D 32 35 0 0 0 0 0 V2000 23.1373 -8.1238 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 19.9710 -9.1794 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.8115 -10.2232 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 21.4545 -9.6615 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 19.1359 -11.7493 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 24.5178 -5.0232 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 24.9998 -3.5395 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 26.5258 -3.2152 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 29.3774 -10.8257 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 27.8174 -10.8257 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 30.1574 -12.1768 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 20.8059 -6.6096 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.3573 -6.7728 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 20.4815 -5.0837 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 19.6466 -7.6536 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 22.9919 -5.3475 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 21.8325 -4.3037 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 18.9978 -4.6017 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 18.1629 -7.1714 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 17.8385 -5.6455 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 24.6974 -8.1238 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 25.4774 -6.7728 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 25.4774 -9.4747 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 27.0374 -6.7728 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 27.0374 -9.4747 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 27.8174 -8.1238 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 29.3774 -8.1238 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 30.1574 -9.4747 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 30.1574 -6.7728 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 31.7175 -9.4747 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 31.7175 -6.7728 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 32.4975 -8.1238 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1 13 1 0 0 0 0 1 21 1 0 0 0 0 2 3 1 0 0 0 0 2 4 2 0 0 0 0 2 15 1 0 0 0 0 3 5 1 0 0 0 0 6 7 1 0 0 0 0 6 16 1 0 0 0 0 7 8 1 0 0 0 0 9 10 1 0 0 0 0 9 11 2 0 0 0 0 9 28 1 0 0 0 0 12 13 1 0 0 0 0 12 14 1 0 0 0 0 12 15 2 0 0 0 0 13 16 1 0 0 0 0 14 17 1 0 0 0 0 14 18 2 0 0 0 0 15 19 1 0 0 0 0 16 17 2 0 0 0 0 18 20 1 0 0 0 0 19 20 2 0 0 0 0 21 22 2 0 0 0 0 21 23 1 0 0 0 0 22 24 1 0 0 0 0 23 25 2 0 0 0 0 24 26 2 0 0 0 0 25 26 1 0 0 0 0 26 27 1 0 0 0 0 27 28 2 0 0 0 0 27 29 1 0 0 0 0 28 30 1 0 0 0 0 29 31 2 0 0 0 0 30 32 2 0 0 0 0 31 32 1 0 0 0 0 M END
References: 8d5ebbe8-ad6d-4116-ab86-fff1386490af, a5a38e01-76af-44ab-96ce-6a0f283c2496

Data from openFDA, FDA's public API. FDA says not to rely on it to make decisions about medical care and to treat every result as unvalidated; confirm against FDA's own record and the product labeling. Not medical or legal advice.