TETRAHYDRO-2-(3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYL-4-PYRIDYL)-2H-1,3-THIAZINE-4-CARBOXYLIC ACID
Also: TIAPIRINOL, tiapirinol [INN]
Open FDA's page for this record- Substance class
- chemical
- Definition type
- PRIMARY
- Definition level
- COMPLETE
- Uuid
- 04f5de48-4bb7-4d25-8848-c1b8b578dc4c
- Version
- 6
- UNII
- 7ZRJ2BMC6X
- Codes
- Uuid
- b06112fb-bd33-4a5e-8885-8db53e6bf13e
- Code
- 14785-50-3
- Type
- PRIMARY
- Url
- https://commonchemistry.cas.org/detail?cas_rn=14785-50-3
- Code system
- CAS
- References
- dbb717ce-f0e3-4acb-bd81-71f730efaca2, 6f2bc042-4f7d-4b13-9953-df6e1cd6ec23
- Uuid
- b18c0667-96fc-4974-a2c2-727f7c6d38f8
- Code
- C91008
- Type
- PRIMARY
- Url
- https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C91008
- Code system
- NCI_THESAURUS
- References
- dbb717ce-f0e3-4acb-bd81-71f730efaca2
- Uuid
- 7e0c39ed-0788-40c9-ae9b-d8c6caae3b5e
- Code
- SUB11009MIG
- Type
- PRIMARY
- Code system
- EVMPD
- References
- dbb717ce-f0e3-4acb-bd81-71f730efaca2
- Uuid
- fe7ef3ac-40de-4711-9805-e7a4d2fc7ff0
- Code
- 2647
- Type
- PRIMARY
- Url
- https://extranet.who.int/soinn/mod/page/view.php?id=137&inn_n=2647
- Code system
- INN
- References
- dbb717ce-f0e3-4acb-bd81-71f730efaca2
- Uuid
- 825c09cb-b420-4e36-8eb2-75b0ae0f9af7
- Code
- CHEMBL2104778
- Type
- PRIMARY
- Url
- https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL2104778
- Code system
- ChEMBL
- References
- dbb717ce-f0e3-4acb-bd81-71f730efaca2
- Uuid
- 9825cc0a-a3bd-4be5-8b64-c662d7c9836c
- Code
- 3084206
- Type
- PRIMARY
- Url
- https://pubchem.ncbi.nlm.nih.gov/compound/3084206
- Code system
- PUBCHEM
- References
- dbb717ce-f0e3-4acb-bd81-71f730efaca2
- Uuid
- 825de636-308b-e3b2-fa15-c7fa54f42430
- Code
- C26017
- Comments
- Dietary Supplement[C1505]|Vitamin, Other
- Type
- CONCEPT
- Url
- https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C26017
- Code system
- NCI_THESAURUS
- References
- 23b194ed-61f2-b938-8c50-f42a06645c7b
- Uuid
- 69202e03-b516-4d77-9d8a-1fc669eb05e9
- Code
- 7ZRJ2BMC6X
- Type
- PRIMARY
- Code system
- FDA UNII
- Uuid
- 9eb3512f-82a3-bbab-f448-6ab99b333d43
- Code
- 100000082179
- Type
- PRIMARY
- Code system
- SMS_ID
- References
- a94a91c8-bced-3f46-08af-4fef0dc22dc9
- Uuid
- 91158e8a-98ca-b48c-7684-f6d28a8a942d
- Code
- DTXSID50864533
- Type
- PRIMARY
- Url
- https://comptox.epa.gov/dashboard/chemical/details/DTXSID50864533
- Code system
- EPA CompTox
- References
- a13ef89a-1fad-b747-d41a-3ad8681485d3
- Relationships
- Uuid
- ec373493-ef7b-4fdf-9eb0-7252cdcf77a3
- Type
- ACTIVE MOIETY
- Related substance
- Uuid
- ed879692-2d91-4b18-a8fa-770cd18787ea
- Refuuid
- 04f5de48-4bb7-4d25-8848-c1b8b578dc4c
- Name
- TIAPIRINOL
- UNII
- 7ZRJ2BMC6X
- Linking ID
- 7ZRJ2BMC6X
- Ref pname
- TIAPIRINOL
- Substance class
- reference
- Names
- Uuid
- dadf91d6-df90-4e2d-96ae-b2e000aa56a2
- Name
- TETRAHYDRO-2-(3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYL-4-PYRIDYL)-2H-1,3-THIAZINE-4-CARBOXYLIC ACID
- StdName
- TETRAHYDRO-2-(3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYL-4-PYRIDYL)-2H-1,3-THIAZINE-4-CARBOXYLIC ACID
- Type
- sys
- Preferred
- false
- Display name
- false
- Languages
- en
- References
- b6d479b5-b303-4c77-975b-cb06af8e79a2
- Uuid
- 055719f3-4493-47de-aeb6-97c5fe26a759
- Name
- TIAPIRINOL
- StdName
- TIAPIRINOL
- Type
- of
- Preferred
- false
- Display name
- true
- Languages
- en
- References
- 3c0141b4-7a45-4358-8076-1c317b68cbfa, 9df6e195-6571-42b4-92ab-937f30e08c50, b6d479b5-b303-4c77-975b-cb06af8e79a2
- Domains
- drug
- Name orgs
- Uuid
- c8748723-eb0e-4dff-bcfa-5f8ea6749e5a
- Name org
- INN
- Uuid
- 3f683d27-8476-4c72-a75f-a7a311bb1198
- Name
- tiapirinol [INN]
- StdName
- TIAPIRINOL [INN]
- Type
- cn
- Preferred
- false
- Display name
- false
- Languages
- en
- References
- 3c0141b4-7a45-4358-8076-1c317b68cbfa
- References
- Uuid
- b6d479b5-b303-4c77-975b-cb06af8e79a2
- Citation
- USP DICTIONARY 2009
- Doc type
- SRS
- Public domain
- true
- Tags
- NOMEN, PUBLIC_DOMAIN_RELEASE, AUTO_SELECTED
- Uuid
- 3c0141b4-7a45-4358-8076-1c317b68cbfa
- Citation
- INN Proposed List 21
- Url
- https://www.who.int/medicines/publications/druginformation/innlists/PL21.pdf
- Doc type
- INN_LIST
- Public domain
- true
- Tags
- PUBLIC_DOMAIN_RELEASE
- Uuid
- dbb717ce-f0e3-4acb-bd81-71f730efaca2
- Citation
- SRS CODE IMPORT
- Doc type
- SRS
- Public domain
- true
- Document date
- 1493390013000
- Tags
- NOMEN
- Uuid
- 0a8c9ead-9c6b-4db5-bc28-21aca5530a99
- Citation
- SRS import [7ZRJ2BMC6X]
- Url
- http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=7ZRJ2BMC6X
- Doc type
- SRS
- Public domain
- true
- Document date
- 1493390013000
- Tags
- NOMEN
- Uuid
- 9df6e195-6571-42b4-92ab-937f30e08c50
- Citation
- TIAPIRINOL [INN]
- Doc type
- SRS_LOCATOR
- Public domain
- true
- Uuid
- 23b194ed-61f2-b938-8c50-f42a06645c7b
- Doc type
- SYSTEM
- Public domain
- true
- Uuid
- 6f2bc042-4f7d-4b13-9953-df6e1cd6ec23
- Citation
- STN
- Doc type
- STN (SCIFINDER)
- Public domain
- true
- Uuid
- a94a91c8-bced-3f46-08af-4fef0dc22dc9
- Citation
- EU-SRS
- Doc type
- EMA LIST
- Public domain
- true
- Uuid
- a13ef89a-1fad-b747-d41a-3ad8681485d3
- Citation
- EPA CompTox
- Doc type
- EPA
- Public domain
- true
- Moieties
- Uuid
- 0a7ce489-691f-4dd3-8acb-2deb98a01b0f
- ID
- 0a7ce489-691f-4dd3-8acb-2deb98a01b0f
- Smiles
- Cc1c(c(c(cn1)CO)C2NC(CCS2)C(=O)O)O
- Formula
- C12H16N2O4S
- Atropisomerism
- No
- Charge
- 0
- Count
- 1
- Stereochemistry
- MIXED
- Defined stereo
- 0
- Ez centers
- 0
- Molecular weight
- 284.333
- Optical activity
- UNSPECIFIED
- Stereo centers
- 2
- Molfile
Marvin 01132100482D 19 20 0 0 0 0 999 V2000 6.9231 -1.4384 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5047 -0.7272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9112 -0.0094 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4929 0.7016 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6679 0.6947 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2495 1.4058 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6561 2.1237 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2613 -0.0231 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.4363 -0.0299 0.0000 C 0 0 0 0 0 0 0 0 0 3 0 0 4.0297 -0.7478 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2048 -0.7546 0.0000 C 0 0 0 0 0 0 0 0 0 3 0 0 2.7864 -0.0436 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1929 0.6743 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0179 0.6811 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 2.7982 -1.4725 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9732 -1.4793 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2166 -2.1835 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.6798 -0.7341 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2731 -1.4520 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 2 3 1 0 0 0 0 2 18 2 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 5 8 2 0 0 0 0 6 7 1 0 0 0 0 9 8 1 0 0 0 0 8 18 1 0 0 0 0 9 10 1 0 0 0 0 9 14 1 0 0 0 0 10 11 1 0 0 0 0 11 12 1 0 0 0 0 11 15 1 0 0 0 0 12 13 1 0 0 0 0 13 14 1 0 0 0 0 15 16 1 0 0 0 0 15 17 2 0 0 0 0 18 19 1 0 0 0 0 M END
- Count amount
- Type
- MOL RATIO
- Average
- 1
- Units
- MOL RATIO
- Uuid
- 7ad07c4f-2ddb-4709-8cab-a886d95bb850
- Structure
- ID
- b616fea6-7b82-48de-92ec-111672a886ab
- Smiles
- Cc1c(c(c(cn1)CO)C2NC(CCS2)C(=O)O)O
- Formula
- C12H16N2O4S
- Atropisomerism
- No
- Charge
- 0
- Count
- 1
- Stereochemistry
- MIXED
- Defined stereo
- 0
- Ez centers
- 0
- Molecular weight
- 284.333
- Optical activity
- UNSPECIFIED
- Stereo centers
- 2
- Molfile
Marvin 01132109262D 19 20 0 0 0 0 999 V2000 4.4363 -0.0299 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0297 -0.7478 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.2048 -0.7546 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7864 -0.0436 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.1929 0.6743 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.0179 0.6811 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 2.7982 -1.4725 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9732 -1.4793 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.2166 -2.1835 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.2613 -0.0231 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9231 -1.4384 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5047 -0.7272 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.9112 -0.0094 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.4929 0.7016 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6679 0.6947 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2495 1.4058 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6561 2.1237 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 5.6798 -0.7341 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.2731 -1.4520 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1 10 1 0 0 0 0 1 2 1 0 0 0 0 2 3 1 0 0 0 0 3 4 1 0 0 0 0 4 5 1 0 0 0 0 5 6 1 0 0 0 0 1 6 1 0 0 0 0 3 7 1 0 0 0 0 7 8 1 0 0 0 0 7 9 2 0 0 0 0 11 12 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 14 15 2 0 0 0 0 15 16 1 0 0 0 0 16 17 1 0 0 0 0 15 10 1 0 0 0 0 10 18 2 0 0 0 0 12 18 1 0 0 0 0 18 19 1 0 0 0 0 M END
- References
- 0a8c9ead-9c6b-4db5-bc28-21aca5530a99, b6d479b5-b303-4c77-975b-cb06af8e79a2, 3c0141b4-7a45-4358-8076-1c317b68cbfa